Pancreatic neuroendocrine tumours: spectrum of imaging findings
نویسندگان
چکیده
منابع مشابه
Whole-genome landscape of pancreatic neuroendocrine tumours
The diagnosis of pancreatic neuroendocrine tumours (PanNETs) is increasing owing to more sensitive detection methods, and this increase is creating challenges for clinical management. We performed whole-genome sequencing of 102 primary PanNETs and defined the genomic events that characterize their pathogenesis. Here we describe the mutational signatures they harbour, including a deficiency in G...
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Five somatostatin receptor (sst) subtype genes, sst(1), sst(2), sst(3), sst(4) and sst(5), have been cloned and characterised. The five sst subtypes all bind natural somatostatin-14 and somatostatin-28 with high affinity. Endocrine pancreatic and endocrine digestive tract tumours also express multiple sst subtypes, but sst(2) predominance is generally found. However, there is considerable varia...
متن کاملAcute pancreatitis secondary to pancreatic neuroendocrine tumours.
CONTEXT Pancreatic neoplasms are an uncommon aetiology of acute pancreatitis. Pancreatic neuroendocrine tumours are a rare subgroup of pancreatic neoplasms. CASE REPORT We report on three patients having acute pancreatitis secondary to pancreatic neuroendocrine tumours, one of them with severe pancreatitis, and review the published cases up to now. Only 22 patients with acute pancreatitis sec...
متن کاملMolecular medicine imaging of neuroendocrine tumours
Neuroendocrine tumours (NETs) are a diverse, highly heterogeneous group of neoplasms derived from endocrine cells found in the neural crest. NETs typically display endocrine metabolism and slow growth, while displaying a wide range of presentations and clinical symptoms. Demonstrating typically small lesions, with varying anatomical localisation, diagnosis is typically in the advanced stages of...
متن کاملAdvances in the treatment of pancreatic neuroendocrine tumours.
Pancreatic neuroendocrine tumours (pNETs) are relatively rare and generally felt to follow an indolent course. But poorly differentiated tumours can behave aggressively with 5-year survival ranging from 31% to 48%. Recent data suggest that patients with pNETs may derive benefit from treatment targeting the molecular changes expressed in this tumour group. This article describes advances in the ...
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ژورنال
عنوان ژورنال: Gland Surgery
سال: 2020
ISSN: 2227-684X,2227-8575
DOI: 10.21037/gs-20-537